I'd say no, as acrylic never 100% dries, where as 2 pack fully cures and is inert. So you can acrylic over 2 pack, but not vice versa. Not 100% sure though, as I only ever do acrylic. Can't acrylic over enamel, as the agressive acrylic thinners will fry it up in a matter of seconds. But you only usually find enamel where people have done nasty aerosol touch ups. If you use aerosols, make sure it actually says acrylic on the label, if not, it's going to be some nasty enamel.
PM Pete on here who commonly posts in Paint & Panel, he'd have the good oil, I believe he is a painter, either currently or in a previous life.
There is also a good Gregory's book on Spray Painting which is very comprehensive, and also has a companion book on panel work, which is also very comprehensive.
Acrylic is very unforgiving on poor preparation, and if any scratches whatsoever, will sink back into the sanding grooves over time (2-3 months). To get around this I go all the way to 1000 grade wet & dry on the primer coat.
Edited by Yella SLuR, 03 February 2007 - 11:33 PM.